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Bone and Joint Anti-Inflammatory Arthritis Support

Factor Five: Osteo-X

Anti-Inflammatory & Arthritis Support

Supplies the necessary calcium, vitamin D, and boron to maintain bone integrity and the proper balance of magnesium and manganese to maintain maximum bone strength.


Contains botanicals to assist in the management of acute inflammation and minerals crucial to collagen and soft tissue maintenance and joint flexibility. An excellent arthritis support formulation.

$20.75 (60 tabs) ORDER NOW!


Research Report


Holistic Recommendations     Validation of Ingredients      References




  • Individuals suffering from arthritis, joint and back pain.

  • Athletes and active individuals desiring protection against sports and work related injuries.

  • All women between 17 and 77 years of age, especially during pregnancy

  • Individuals with osteoarthritis, cartilage and/or tendon/ligament strain, and those with low bone density.



Take 2 tablets daily with evening meal as a precaution or 2 tablets twice daily with meals for nutritive support to relieve osteoarthritis and joint inflammation.
Take 2 tablets three times daily with meals for 10 days following trauma such as bone breaks or fractures.
(May be taken at night on an empty stomach as a sleep aid).


Do not take this product simultaneously with antacids, diuretics or medications such as Dilantin, corticosteroids, Phenobarbital, lithium, tetracycline or thyroid hormone as these substances counteract and deplete calcium. Take at least two hours apart.

Important notes: Calcium antacids are often recommended as a source of calcium. This is ludicrous as antacids change the pH of the stomach and intestines, which alters the digestion efficiency of most enzymes.

Many sources of calcium supplementation have been found to contain lead, including carbonate, dolomite and bone meal. Additionally, these forms of calcium are frequently difficult for the body to absorb.

Calcium citrate is readily absorbed, even by individuals who are severely deficient in stomach acid, and has the added benefits of chelating out heavy metals from the body, preventing recurrent kidney stones, and augmenting treatment of urinary tract infection.


This product utilizes the citrate form of calcium exclusively.



Holistic Recommendations

Both nutritional therapy and chiropractic share the philosophy that the body has the inherent ability to heal itself with the proper resources and treatment procedures.


Bone - formed from collagen fibers and comprised of hydroxyapatite crystals - is a living substance and one of the most active tissues in the body! Bone is constantly being dissolved and rebuilt (a process known as remodeling) and requires the proper nutrients to remain strong and healthy.


Osteoarthritis affects 80% of persons over the age of 50 and Osteoporosis affects 25 million people of all ages, clearly indicating that most individuals are not meeting the nutritional requirements necessary to maintain strong bones and supporting connective tissues.45


It is therefore not surprising that most Americans complain of arthritis, back problems, and experience frequent injuries.


The nutrients in Factor Five: Osteo-X act to protect against altered or defective collagen synthesis by enhancing collagen matrix integrity and decreasing the enzymatic breakdown of collagen necessary for the formation of connective tissue in ligaments and bones.


The ingredients in this product work synergistically to support the body's natural ability to heal itself and may be safely employed 


As Nutritive Support for Injury and Back Pain


It is well established that the ingestion of specific nutrients can help accelerate the healing process and provide above normal healing rates.46 Patients recovering from bone fractures require 25% more calories than normal. In cases of major trauma, tissue damage and/or inflammation, the calorie need goes up by 30 to 55%.47 Yet, in a modern Houston hospital, physicians found that all of the 129 surgery patients examined had at least one indication of significant nutritional depletion, with 42% being clinically malnourished!48


It is important to supply the body with enough energy (calories) to meet the increased metabolic demands caused by injuries during the three phases of injury rehabilitation:


Phase I - Inflammation which lasts from 48 to 72 hours but can vary. Inflammation occurs when a part of the body reacts to trauma, caused by strain, injury, or arthritis, or infection caused by bacteria. Symptoms include pain, heat, swelling, and redness..


The primary nutritional remedy to ameliorate inflammation is a combination of proteolytic enzymes (proteases) such as bromelain, papain, lipase and amylase49 which is incorporated into Factor Five: Osteo-X under the proprietary trade name Biozyme-10.


Depending on the type of injury, oral use of proteolytic enzymes can reduce healing times by up to 50%50 while the herbal extracts of ginger and licorice root act as a natural cortisone in blocking inflammation and reducing pain.


Phase II - Repair usually lasts from 48 hours to about six weeks during which time collagen production and formation occurs. Maintaining adequate levels of vitamins and minerals is crucial during this repair phase as any deficiency can adversely effect healing.51 Calcium, magnesium, manganese and boron are especially important.52


As inflammation can generate large amounts of free radicals, a full spectrum of antioxidant nutritional support may also be utilized.53


Phase III - Remodeling lasts a minimal of three weeks and may require up to twelve months to accomplish in certain injuries. During this phase the strengthening of connective tissue and muscle occurs through hyperplasia and hypertrophy. Connective tissues include cartilage, tendons, ligaments and bone.


The remodeling phase is dominated by anabolic repair which is enhanced by supplying the nutrients necessary for growth. These include Factor Five: Osteo-X at the suggested nutritive support dosage and Factor Seven: Digestin at the daily recommended dosage.


As a Preventative & Treatment for Osteoporosis


Osteoporosis - or porous bones - is a disease characterized by excessive loss of bone mass resulting in increased fractures, loss of height, pain in the hip and back, and spinal curvature. The disease is silent and offers no early symptoms as bones become porous over a period of many years. Around age 40, bone mass begins to gradually diminish in both sexes, with a continuous loss over adult life at a mean rate of 1.2% per year. However, osteoporosis is not a normal part of aging. It is a normal part of degeneration caused by inadequate nutrition!54


Available evidence indicates that those with a lifetime history of adequate calcium intake are less susceptible to osteoporosis at advanced ages.


Osteoporosis, however, is more than merely a lack of dietary calcium. Rather, it is a complex condition involving hormonal, lifestyle, nutritional and environmental factors.55


Several risk factors are associated with osteoporosis, including the following:


1) Genetics such as family history of osteoporosis.


2) Sex - women are three times more likely than men to develop osteoporosis because they have less bone mass to begin with.


3) Body type - small body frame or slender build are more prone toward the disease.


4) Inadequate amounts of calcium and Vitamin D in the diet.


5) Hormonal factors - Osteoporosis is most commonly seen after menopause (surgical or natural), when the protective effect of estrogen in bone has been lost. In younger women, any interruption of menstruation for an extended period results in bone loss, such as anorexia nervosa, bulimia, and menstrual irregularities due to excessive exercise.


6) Sedentary lifestyle - regular weight-bearing exercise is important for achieving and maintaining good bone mass.


7) Smoking affects the protective action of estrogen in bone. Alcohol can block calcium absorption and bone growth.


8) Drugs such as cortisone, Dilantin, methotrexate, heparin and excess thyroid medication can all affect bone mass.


9) Medical conditions such as chronic kidney disease, overactive thyroid, malabsorption, and certain types of intestinal surgery can place the patient at higher risk.


If the individual exhibits any of the above risk factors, or has undergone trauma, surgery, or bone fractures, he or she should be strongly encouraged to practice the following preventative and remedial recommendations:



Recommendations for the Rejuvenation of Bone and Connective Tissue, Prevention of Osteoporosis and the Arthritic Relief of Joint Inflammation


1) Take Factor Five: Osteo-X supplementation as directed. One gram (1,000 mg) of calcium daily can halt or even reverse bone loss in humans.56


2) Exercise! Sedentary lifestyle strongly encourages bone mineral loss. After only a few months in space, astronauts can lose up to 25,000 mg of bone calcium.57


3) Relax! Practice stress management. Worry and tension can cause both lowered calcium absorption and increased calcium loss while triggering arthritic inflammation.58


4) Take a 15 minute sunbath twice a week! Vitamin D is mandatory for the absorption and use of calcium and preventing bone erosion.59


5) Maintain weight control. Excess poundage stresses the joints and exacerbates inflammation. Symptoms of osteoarthritis often subside with a return to a healthy weight.60


6) Develop a good diet of fresh fruits and vegetables, oatmeal, brown rice and whole grains. Eat fish such as salmon, sardines, flounder and cod in lieu of red meat.61


7) Hard water can provide up to 375 mg of calcium per liter of drinking water!62 By comparison, milk provides about 288 mg of calcium per cup. Further, pasteurization destroys the useful enzymes in milk, leaving it dead, inert, and useless, and thus may be irritating to the lining of the intestines.63


8) Reduce or Avoid tobacco, alcohol and coffee as these substances deplete bone minerals and exacerbates inflamed joints.64


9) Avoid the use of cortisone, anti-seizure medication or anticoagulants whenever possible.65


10) Avoid phosphate-containing soft drinks, additives, and high-protein animal foods.66 When the calcium to phosphorus ratio goes above 1:1.25 in phosphorus, then most other efforts to prevent osteoporosis are likely in vain.


11) Eat a wide variety of foods. Individuals who eat a varied diet have a better nutrient intake than those whose diet remains staid.67


12) Reduce salt intake. Urinary calcium increases about 23mg for every teaspoon of salt consumed which is sufficient to dissolve one percent of the skeleton annually or ten percent in a decade!68


As a Support & Preventative for Osteoarthritis


Osteoarthritis or degenerative joint disease is the most common form of arthritis affecting over 40 million Americans, including 80% of people over 50 years of age.69


The weight-bearing joints and joints of the hands are principally affected, however, spinal osteoarthritis is very common and may result in compression of nerves and blood vessels, causing pain and vascular insufficiency.70 The bone joint is a marvel of engineering. The joint is connected by the tough, fibrous proteins collagen and elastin and lubricated by synovial fluid that is so slippery even modern chemistry cannot duplicate its lubricant abilities. Since bone joints are built from, and repaired by, dietary nutrients, nutrition can be utilized to help many arthritics.


Studies and evaluations of osteoarthritis - from the earliest signs to the most advanced stages - indicate that cellular and tissue response to this disease is purposeful and aimed at repair of the damaged joint structure. Based upon such analysis, it appears the process contributing to osteoarthritis may be stopped and sometimes reversed.71


1) Take Factor Five: Osteo-X in the dosage recommended for relief of back pain and joint inflammation. The herbal extracts of ginger and licorice root together with extract of wintergreen and the amino acid DL-phenylalanine will synergistically act to reduce inflammation and pain.


2) Avoid non-steroidal anti-inflammatory drugs (NSAIDS) such as aspirin, ibuprofen (Motrin, Advil, Nuprin), fenoprofen (Nalfon), and related products.


Numerous clinical studies have shown that NSAIDS actually accelerate osteoarthritis and increase joint destruction.72, 73 This is a classic example where current medical treatment simply suppresses the symptoms while actually promoting the disease process!


3) Take a multivitamin supplement in the dosage recommended as vitamin E has an ability to inhibit the enzymatic breakdown of cartilage as well as stimulate cartilage synthesis;74 folic acid, niacin, and vitamin C has a positive effect on cartilage;75 and vitamin A is required for the synthesis of normal collagen and maintenance of cartilage structures.76


4) Avoid all simple, processed and concentrated carbohydrates and fats.


5) Avoid plants of the solanaceae family, such as tomatoes, potatoes, eggplant, peppers and tobacco).


6) Take physical therapy regularly including ultrasound, isometric exercises and especially short-wave diathermy.77


As a Support for Rheumatoid Arthritis


Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the entire body but especially the synovial membranes of the joints. It is a classic example of an "autoimmune disease", a condition where the body's immune system attacks its own tissue.


Although much less common than osteoarthritis - somewhere between 1 and 3 percent of the population is affected - the rheumatoid form is usually much more severe.


Because many of the pathologic processes involved in this disease are temporary and spontaneous, improvement often occurs. As a result, it is common for RA to be exploited by hucksters who are eager to offer "the latest cure".78


Unfortunately, rheumatoid arthritis is a disease that has no known cure, no prevention, and no specific cause at this point in time. However, RA can be managed and ameliorated in many cases.79


An assessment of the nutritional status of patients with rheumatoid arthritis is very important. The inflammatory process in RA is accompanied by an elevated metabolic rate that leads to increased nutritional requirements.80


Individuals with rheumatoid arthritis are frequently underweight, in contrast to those with osteoarthritis who are often overweight.81


While RA is an autoimmune reaction, what triggers this reaction remains largely unknown. What is currently known is that individuals with RA have increased intestinal permeability to dietary and bacterial antigens as well as alterations in bacterial flora.82, 83 Thus, diet has been strongly implicated in RA in regards to both cause and amelioration.


Generally, RA is not found in societies that eat a more primitive diet of whole foods, vegetables, and fiber and is found at a relatively high rate in modern societies consuming a diet rich in refined carbohydrates, sugar, meat, and saturated fats.84


1) Joint pain can be a manifestation of a food allergy. Elimination of allergic foods has been shown to offer significant benefit to some individuals with RA.85 However, such elimination should be well documented with blinded food challenges so that foods are not eliminated unnecessarily simply because their consumption happened to coincide with an arthritic flare-up.


2) Sodium restriction is recommended as some RA patients retain salt and water because of immobility resulting from joint pain or medication.86


3) Take Factor Five: Osteo-X in the suggested trauma dosage during RA flare-up of joint pain. Product ingredients include the well documented anti-inflammatory herbal extracts of ginger and licorice root, together with the proteolytic enzyme bromelain. These ingredients have been found to be useful in both rheumatoid and osteoarthritis.87, 88, 89


4) Adhere to the recommendations outlined for Rejuvenation of Bone and Connective Tissue, Prevention of Osteoporosis, and the Relief of Joint Inflammation listed above.


As a Remedy for Relief of Heartburn, Nausea & Motion Sickness


Heartburn is a burning sensation in the stomach. It often occurs when hydrochloric acid (HLC), utilized by the stomach for digestion, backs up into the esophagus.


Heartburn may be caused by either an excess of HCL or a shortage of HCL in the stomach. Many new OTC antacids are HLC reducers which often provide relief of symptoms by masking the underlying cause!90


It is recommended you take a tablespoon of apple cider vinegar or lemon juice. If the heartburn recedes, then the patient needs more stomach acid. If symptoms become worse, you have an excess of HCL.


1) At the first sign of heartburn, drink a large glass of water which often cures the problem.


2) If you have an excess stomach acid, take Factor Five: Osteo-X in the dosage recommended. If you have a shortage of HCL, relief can be obtained by sipping one tablespoon of apple cider vinegar mixed with water while eating.


3) Avoid excessive consumption of spicy or fatty and fried foods, alcohol, coffee, citrus fruits, chocolate, and tomato-based foods which are prone to cause heartburn.


4) Avoid OTC antacid products which contain sodium and aluminum. Excess sodium can aggravate hypertension and excess aluminum has been implicated in Alzheimer's disease.


Motion Sickness symptoms range from severe headache, dizziness, cold sweats, and loss of desire for food to nausea and vomiting while flying, sailing, or traveling long distances in automobiles or trains.


Nausea and vomiting may result from a deficiency of magnesium or vitamin B-6, however, these symptoms may also indicate the presence of liver problems, an infected appendix, low blood sugar, or food poisoning. A physician should be consulted if such symptoms persist.91


The combination of ginger and licorice root extracts have long been determined to diminish the symptoms of nausea from motion sickness, morning sickness, and the amelioration of vertigo and dizziness.92 In fact, studies have demonstrated that ginger root by itself is more effective than Dramamine in preventing motion sickness.93


At the first signs of nausea, motion, or morning sickness, the patient should take the recommended dosage of Factor Five.



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Two Tablets Equals:

B-6 (Pyridoxine HCL)
Vitamin D3 (cholecalciferol)
Calcium (as Calcium citrate)
Magnesium (oxide)
Vitamin C (Calcium ascorbate)
Manganese (gluconate)
Copper (lysinate)
Boron (glycinate)
Zinc gluconate
DL-Phenylalanine (amino acid)
Ginger root (Zingiber officinale) extract equal to
Licorice root (Glycyrrhiza Glabra) extract equal to
Wintergreen (Gaultheria Procumbens) extract equal to

  25 mg.
400 I.U.
600 mg.
300 mg.
100 mg.
  10 mg.
    1 mg.
    3 mg.
    5 mg.
100 mg.
250 mg.
150 mg.
  50 mg.


Validation of Ingredients

PYRIDOXINE (VITAMIN B-6) is necessary in the production of hydrochloric acid. Inadequate stomach acid, a common problem in older adults, lowers efficiency in absorbing calcium.1 Vitamin B-6 might also aid in the healing of bones after a fracture.2 A deficiency of vitamin B-6 can cause the departure of needed calcium from the body.3


Pyridoxine inhibits the formation of a toxic chemical called homocysteine which has been implicated in a wide variety of conditions including arteriosclerosis and osteoporosis.4 In-creased homocysteine concentrations in the blood have been demonstrated in postmenopausal women and are thought to play a role in osteoporosis by interfering with collagen cross-linking.5


VITAMIN D3 (CHOLECALCIFEROL) is essential to the absorption of dietary calcium from the intestine and deposition of calcium into bone. A long-term loss of this vitamin is associated with calcium loss and bone deterioration.6 A study of elderly patients in a 120-bed nursing home found that many suffered from osteomalacia, a painful bone-softening disease caused by a vitamin D deficiency.7 A clear correlation was found indicating the longer the confinement and subsequent lack of vitamin D, the more often this painful bone wasting occurred in patients.


NOTE: Individuals who spend a consistent amount of time in the sun during the entire year are not particularly prone to develop melanomas, according to the 1985 report "Sunlight and skin cancer" in the New England Journal of Medicine. Individuals prone to skin cancer are those who normally live in temperate climates, spend most of their time indoors, and then expose themselves to intense sunlight by spending occasional weekends on the beach or winter vacations in the tropics. Consistency and moderation are the keys to maintaining healthy bones without risking cancer.


CALCIUM (AS CALCIUM CITRATE) is necessary to prevent osteoporosis, hypertension, tetany (muscle spasms such as cramps) and insomnia.8 This mineral is vital for the normal blood clotting mechanisms that begin the process of wound healing.9 Calcium also helps maintain all cell membranes and aids in the maintenance of connective tissue.10 Restoration and maintenance of bone tissue is observed in people who consume, over several years, a high-calcium diet plus at least 750 mg of calcium/day from supplements and 375 IU/day of vitamin D.11


At present, calcium citrate appears to be the best form of calcium to supplement with, in regards to both absorption and decreased risk of developing kidney stones.12, 13 In addition, citrate has the ability to chelate out heavy metals, prevent recurrent kidney stones, augment treatment of urinary tract infection and promote diuresis.14, 15


MAGNESIUM (OXIDE) supplementation appears to be as important as calcium supplementation. Individuals with osteoporosis have lower magnesium content than people without osteoporosis.16 Magnesium is important in the development and maintenance of strong bones. When magnesium is deficient, calcium is lost.17 Magnesium also plays a role in the formation of bone and in carbohydrate and mineral metabolism.18


A study reported by the American Journal of Clinical Nutrition (vol 56, 1992) found that when two groups of untrained subjects underwent a seven-week strength training program, the group that received a magnesium supplement increased their strength 28.6% while the placebo group increased only 10.5% - a significant difference.


Magnesium supplementation prevents sore muscles, cramps, and elevated blood pressure, allowing patients to walk with out pain.19


VITAMIN C (CALCIUM ASCORBATE) functions as an important antioxidant which increases superoxide dismutase (SOD) levels, decreases histamine levels, which dry the joints, and provides anti-inflammatory action.20, 21 Studies have confirmed that vitamin C has a positive effect on cartilage22, 23 and, in fact, an excess of ascorbic acid is necessary in human chondrocyte protein synthesis to mitigate cartilage erosion.24 Deficient vitamin C intake is common in the elderly, resulting in altered collagen synthesis and compromised connective tissue repair.25


MANGANESE (GLUCONATE) participates in the formation of connective tissues, bone growth and in the digestion of proteins. A long term deficiency of manganese is associated with calcium loss from bone because of this trace mineral's role in bone metabolism.26 Before other exotic connective tissue supplements such as chondroitin sulfate and glucosamine, there was manganese which is necessary to activate enzymes needed for collagen and proteoglycan synthesis.27


COPPER (LYSINATE) is required for the synthesis of normal collagen and maintenance of cartilage structures.28 Copper is a co-worker with zinc. When researchers gave injections of zinc-copper superoxide dismutase directly into human arthritic joints, the symptoms improved.29


Arthritis victims often have higher than normal copper levels in their arthritic joints. Years ago, this was interpreted that copper caused arthritis. Now, however, scientists find the opposite to be true. In a double-blind study, osteoarthritis patients whose copper bracelets were replaced with placebo bracelets experienced a significant deterioration in their condition.30


BORON (GLYCINATE) aids in the absorption of calcium. A recent study conducted by the U.S. Department of Agriculture indicated that within eight days of supplementing the diet with 3 mg of boron, a test group of postmenopausal women lost 40 percent less calcium and one-third less magnesium through their urine.31


ZINC GLUCONATE can inhibit the inflammation process that occurs in arthritis by suppressing the release of histamine from mast cells.32 Arthritis victims usually have lower than normal zinc levels in their blood.33 In a double-blind study using arthritis patients, zinc supplementation provided noticeable improvement in morning stiffness, joint swelling, walking time, and the patients' own impression of their condition.34


DL-PHENYLALANINE is a mixture of the amino acids D and L-phenylalanine. The D form may prevent breakdown of the brain's natural narcotics and has been shown to relieve the chronic pain of osteoarthritis, rheumatoid arthritis, low back pain and migraine headaches.35 The L-form is the precursor of norepinephrine and dopamine. DL-phenylalanine is effective in the control of pain, especially in those with arthritis.36


GINGER ROOT (ZINGIBER OFFICINALE) FROM EXTRACT produces anti-inflammatory activity similar to non-steroidal, anti-inflammatory drugs. It interferes with the manufacture of prostaglandin and thus blocks inflam-mation.37 Ginger ameliorates symptoms of nausea, motion and morning sickness, vertigo, dizziness and stomach disorders.38 Ginger root helps the body recover from the effects of stress and fatigue more rapidly than otherwise.39


LICORICE ROOT (GLYCYRRHIZA GLABRA) FROM EXTRACT possesses substantial anti-inflammatory properties and is widely utilized to ameliorate stiff, inflamed and sore muscles and joints due to arthritis, rheumatism, lupus, gout and bursitis.40, 41, 42 Licorice root extract contains a triterpene saponin called glycyrrhizin which exhibits a powerful cortisone-like effect. European researchers concluded several decades ago that licorice root extract has none of the side effects associated with the use of cortisone and hydrocortisone drugs yet is every bit as effective.43


WINTERGREEN (GAULTHERIA PROCUMBENS) FROM EXTRACT has long been used to combat muscle pain, arthritis, and rheumatism as this herb consists predominately of methyl salicylate, a close relative of aspirin. In contrast to aspirin, however, small amounts relieve stomach indigestion instead of causing it.44


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1. Recker, R, New England Journal of Medicine, vol 313, p.70, July 1985

2. Albanese, A, Nutritional Rep, vol 4, p.84-85, 1986

3. Kirschman, J, et al., Nutrition Almanac, p.107, 1984

4. Barker, H, et al., J. Am. Geriatrics Society, vol 10, pp. 444-50, 1979

5. Brattstrom, LE, et al., Metabolism, vol 34, pp. 1073-7, 1985

6. Osteoporosis Consensus Conference, J. Am. Med. Assoc,. vol 252, pp.799-802, 1984

7. Thomas, W, et al., J. Florida Medical Assoc., Jan 1992

8. Somer, E, Essential Guide To Vit. and Min., HarperCollins Publishers, New York, NY, 1992

9. Kanofsky, JD, et al., New England J. of Medicine, p. 173, July 16, 1981

10. Rottka, H, et al., International J. of Vit. & Nutritional Research, vol

51, pp. 373-79, 1981

11. Jackson, T, et al., Postgraduate Medicine, vol 75, pp. 119-125, 1984

12. Recker, R, New England J. of Medicine, vol 313, pp. 70-3, 1985

13. Nicar, MJ, et al., J. Clinical Endocrinology and Metabolism, vol 61, pp. 391-3, 1985

14. Pak, CY, et al., Annals of International Medicine, vol 104, pp. 33-7, 1986

15. Johansson, G, et al., Journal of Urology, vol 124, pp. 770-4, 1980

16. Cohen, L, et al., Israel J. of Medical Science, vol 17, pp. 1123-5, 1981

17. Brecklin, M, The Practical Encyclopedia of Natural Healing, 1983

18. Morgan, K, et al., J. American College of Nutrition, vol 4, pp. 195-206, 1985

19. Neglen, P, et al., VASA, vol 14, pp. 285-88, 1985

20. Subramanian, N., Agents and Actions, vol 8, pp. 484-7, 1978

21. Levine, M., New England J of Med, vol 314, pp. 892-902, 1986

22. Krystal, G, et al., Arthr. Rheum., vol 25, pp. 318-25, 1982

23. Prins, A. P., et al., Arthr. Rheum., vol 25, pp. 1,228-32, 1982

24. Ibid

25. Bates, C. J., Clinical Sci. Molecular Med., vol 52, pp. 535-43, 1977

26. Saltman, P, et al., Nutritional Rep, vol 5, pp. 33-40, 1987

27. Bucci, L, Nutrition Applied to Injury Rehab. and Sports Medicine, CRC Press, Boca Raton, FL 1995

28. Krause, M. V., et al., Food, Nutrition and Diet Therapy, 7th Ed.,

W.B. Saunders, Philadelphia, PA, pp. 677-9, 1984

29. Huber, W. et al., Clinics in Rheumatic Disease, vol 6, p. 465, 1980

30. Walker, BC, et al., Agents and Actions, vol 6, p. 454, 1976

31. Balch, J, Prescription for Nutritional Healing, Avery Publishing, Garden City Park, NY, 1990

32. Chapil, HR, Medical Clinics of North America, vol 60, p. 799, 1976

33. Niedermeier, W, et al., Journal of Chronic Diseases, vol 23, p. 527, 1971

34. Simkin, P. A., Lancel, vol ii, p. 862, 1963

35. Bonica, J, et al., Advances in Pain Research and Therapy, vol 5, Raven Press, NY, NY, 1983

36. Balch, J, Prescription for Nutritional Healing, Avery Pub., Garden City Park, NY, 1990

37. Weiner, M, Weiner's Herbal, Quantum Books, Mill Valley, CA, 1992

38. Mowrey, DB, et al., The Lancet, pp. 655-57, Mar 20, 1982

39. Suzuke, Y, et al., Folia Pharmacologia Japonica, vol 75, no 7, pp. 731-46, 1970

40. Tangri, KK, et al., Biochemical Pharmacology, vol 14, no 8, pp. 1277-81, 1965

41. Cappelletti, EM, et al., Journal of Ethnopharmocology, vol 6, no 2, pp. 161-90, 1982

42. Armanini, D, el al., Clinic Endocrinology, vol 19, no 5, pp. 609-12, 1983

43. Finney, SH, et al., J. of Pharmacology and Pharmacodynamics, vol 10, no 10, pp. 613-20, 1958

44. Kelville, K, Herb Encyclopedia, Grange Books, London, England, 1991


Validation of Holistic Recommendations


45. Robins, SL, et al., Pathologic Basis of Disease, W.B. Saunders, Philadelphia, PA, pp. 1356-61, 1984

46. Chandra, RK, et al., British Medical Journal, vol 6, pp. 119-22, 1988

47. Souba, WW, et al., Modern Nutrition in Health and Disease, 7th Ed., Lea & Febiger, Philidelphia, PA, pp. 1306-36, 1988

48. Jensen, JE, et al., Journal of Bone and Joint Surgery, vol 64A, p. 1263, Dec 1982

49. Walker, JA, et al., Medicine and Science in Sports and Exercise, vol 24, no 1, pp. 20-25, 1992

50. Bucci, LR, Stiles, J, "Sports injuries and proteolytic enzymes", Today's Chiropractic, vol 16, no 1, pp. 31-34, Mar 1987

51. Burtis, G, et al., Applied Nutrition and Diet Therapy, W.B. Saunders, Philidelphia, PA, pp. 498-515, 1988

52. Sherrod, CW, et al., Chiropractic Sports Medicine, vol 2, no 3, pp. 73-7, 1988

53. Bucci, L, Chiropractic Rehabilitation Journal of the CRA, pp. 17-20, Aug 1989

54. Schmid, R, Traditional Foods Are Your Best Medicine, Ballantine Books, New York, NY, 1987

55. Pizzorno, JE, A Testbook of Natural Medicine, John Bastyr College Pub., Seattle, WA, 1985

56. Albanese, AA, et al., American Family Physician, vol 18, no 4, p. 162, Oct 1978

57. Korcak, M, Journal of the American Medical Assoc., vol 247, p. 1106, Feb 1982

58. Rambaut, PC, et al., The Lancet, p. 1050, Nov 1985

59. Garrison, R, et al., The Nutrition Desk Reference, p. 59, 1985

60. Nordin, BE, et al., Am. J. of Clinical Nutrition, vol 42, p. 470, Sept 1985

61. Quillin, P, Healing Nutrients, Vintage Books, New York, NY, p. 315, 1987

62. Darlington, LG, et al., The Lancet, p. 236, Feb 1986

63. Cort, A, Our Healing Birthright, Healing Arts Press, Rochester, VT, p. 87, 1990

64. Quillin, P, Healing Nutrients, Vintage Books, New York, NY, p. 312, 1987

65. Balch, J, Prescriptin for Nutritional Healing, Avery Pub, Garden City Park, NY, p. 256, 1990

66. Ibid

67. Randell, E, et al., J. Am. Dietetic Assoc., vol 85, p. 830, July 1985

68. Journal of Nutrition, vol 123, p. 1615, 1993

69. Robbins, SL, et al., Pathologic Basis of Disease, W.B. Saunders, Philadelphia, PA, pp. 1356-61, 1984

70. Petersdorf, R, et al., Harrison's Principles of Internal Medicine, McGraw-Hill, New York, NY, pp. 517-24, 1983

71. Bland, JH, et al., Sem. Arthr. Rheum., vol 14, pp. 106-33, 1984

72. Brooks, PM, et al., J. Rheumatol, vol 9, pp. 3-5, 1982

73. Newman, WM, et al., The Lancet, vol ii, pp. 11-13, 1985

74. Schwartz, ER, Int. J. Vit. Nutr. Res., supplement 26, pp. 141-6, 1984

75. Krystal, G, et al., Arth. Rheum., vol 25, pp. 318-25, 1982

76. Krause, MV, et al., Food, Nutrition and Diet Therapy, 7th Ed, W.B. Saunders, Philadelphia, PA, pp. 677-9, 1984

77. Vanharantha, H, Am. J. Phys. Medicine, vol 61, pp. 59-65, 1982

78. Mahan, LK, et al., Krause's Food, Nutrition & Diet Therapy, 8th Edition, W.B. Saunders Co., Philadelphia, PA, pp. 692 & 694, 1992

79. Ibid

80. Darlington, LG, et al., Lancet, vol 1, p. 236, 1986

81. Touger-Decker, R, Journal of American Diet Assoc, vol 88, p. 327, 1988

82. Smith, M.D. et al., Journal of Rheumatology, vol 12, pp. 299-305, 1985

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