Natural Alternative to Hormone Replacement Therapy Factor Ten: Femtrac
	A phyto-estrogen female health formulation which provides a natural alternative to hormone replacement therapies (HRT).  Synergistically formulated and balanced to supply the phyto-estrogens and other nutrients to maintain hormonal balance and support gynecologic health.
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Research Report

Holistic Recommendations     Validation of Ingredients      References

REASONS TO CONSIDER (OVERVIEW)

• Women concerned about synthetic Hormone Replacement Therapy.

• Women experiencing menstrual cramps (dysmenorrhea).

• Women suffering from premenstrual syndrome (PMS).

• Females experiencing perimenopause or menopause symptoms.

• Females serious about improving vitality, body definition, and resistance to female disorders.

DOSAGE & DIRECTIONS

Take 2 capsules in the morning and 2 capsules at noon or early evening for best results. Do not exceed 6 capsules per day. Do not take in late evening as product raises basal metabolic rate and may cause sleeplessness.

Synthetic hormones have been shown to be addictive in some women. It may require 30 to 90 days on an every other day dosage alternating between the synthetic hormone and Factor Ten: Femtrac to wean the patient. After 90 days, following the recommendations in this report, the patient may be able to discontinue the use of synthetic hormones entirely.

 

Factor Ten: Femtrac provides phytoestrogens and other nutrients that complement the rhythmic patterns of change a woman's reproductive system follows throughout her life.

 

Factor Ten: Femtrac may be readily combined with other Factor Series formulations to assist the body in rebounding from specific female disorders.

 

PROTOCOL FOR WEANING YOURSELF FROM SYNTHETIC TO NATURAL HORMONE REPLACEMENT THERAPY

Considering the addictive nature of synthetic hormones, Titan Laboratories has developed a specific protocol for weaning the patient off these side-effect laden drugs:

 

Month One. Take regular dosage of synthetic hormone. Also take 2 capsules twice daily of Factor Ten: Femtrac with one tablet (25 mg) of Factor Four: DHEA-Forte. Be sure to space dosages two hours apart from the ingestion of synthetic hormone. (Studies now show that women placed on DHEA experienced a 2-fold increase in progesterone levels and symptoms such as hot flashes were ameliorated.)

 

Month Two. Reduce dosage of synthetic hormone to every other day while maintaining the above dosage levels of Factor Ten: Femtrac and Factor Four: DHEA-Forte.

 

Month Three. Reduce dosage of synthetic hormone to every third day while maintaining dosage levels of Factor Ten: Femtrac and Factor Four: DHEA-Forte.

 

Month Four. Discontinue synthetic hormone while maintaining dosage levels of Factor's Ten and Four.

 

CONTRAINDICATIONS & PRECAUTIONS

Reduce dosage if body fat falls below 19 percent. (The ideal body fat range for women is between 19-26%).

This product has no known contraindications, however, do not take supplements at the same time as medications. If both must be taken with food, take them at different meals.

 

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Holistic Recommendations

 

Dispelling the Hormone Replacement Myths.

 

There are many different types of phytoestrogens that are structurally similar to human endogenous estrogens. Very often phytoestrogens mimic mammalian reproductive hormones as a defense mechanism, i.e., the plants modulate the fertility of the herbivores that feed on them.₉₀Ö

The relevance to humans is that there is a wisdom in nature. After middle age, women have low reproductive hormones because it is not wise for them to continue reproduction. The notion of modern medicine that all women over menopausal age suffer from "nature's error" and are estrogen-deficient is erroneous.₉₁

The natural design of a woman's body is to produce the two hormones, estrogen and progesterone, in very sensitive and precise balances so reproductive ability is maximized. Once a woman is past her childbearing years, her need for both these hormones is minimal!

Osteoporosis is not an estrogen deficiency disease. Osteoporosis begins a decade or more before estrogen levels fall and is linked to may factors including unhealthy lifestyles, low androgen levels (such as DHEA), and high homocysteine.

It is excess protein in the form of meat and dairy products that contribute the most to bone loss. An acidic condition is created in the blood and the body pulls out calcium from the bones to neutralize it. Epidemiological studies confirm that vegetarians and Japanese women have a much lower incidence of osteoporosis and fractures.₉₂ (The current high protein diet fad that many women are on is going to exacerbate this problem!)

Further, all estrogen-containing medications - including hormone replacement therapy (HRT) - deplete magnesium. This magnesium deficiency causes the body to leach magnesium out of the bone stores to normalize the cal/mag ratio in the blood. Instead of preventing osteoporosis, this can cause skeletal deterioration.₉₃

The Factor Ten formulation includes the herbal extract Centella asiatica which increases the formation of chondroitin sulfate in bone.₉₄ The addition of magnesium chelate helps maintain the cal/mag blood ratio to counter skeletal deterioration.

Estrogen does not prevent cardiovascular disease. Ample evidence exists showing that the opposite is true! Research reveals that high doses of estrogens are thrombogenic (blood-clotting) and may cause hypercoagulability, thereby increasing the risk of heart attack and stroke.₉₅ Estrogen further compromises the integrity and function of cell membranes by allowing the loss of potassium and magnesium.₉₆

Progesterone prevents female cancers only in those cases where women are taking synthetic estrogen! There is abundant evidence that pharmaceutical estrogens are linked to reproductive cancers such as breast and uterus. In Japan, the incidence of breast cancer is very low in areas where a traditional diet high in phyto-estrogens is consumed. In fact, research among Finnish and Japanese populations has found that phytoestrogens may in particular protect against breast cancer.₉₇

It is the view of many holistic health practitioners that post-menopausal women are a source of unethical pharmaceutical experimentation.₉₈

Phytoestrogens enhance Female Health Without the Risks of Synthetic Estrogens and Progestins.

Phytoestrogens, such as Angelica sinesis, Licorice root, Black cohosh, Suma, Bioflavonoids and metabolic enzymes such as lipase, papain and bromelain may reduce menopausal symptoms, support bone mineralization, and decrease the risk of uterus and breast cancers.₉₉

Phytoestrogens, because they exert low estrogenic effects, assist the body in establishing hormonal homeostasis. If estrogen levels are low, phytoestrogens will boost estrogen effects. If estrogen levels are high, since phytoestrogens bind to estrogen receptor sites thereby competing with endogenous estrogen, estrogen effects will be decreased. Because of this balancing effect, their historical use has been for conditions of estrogen excess (PMS) and estrogen deficiency (menopause).₁₀₀

Premenstrual syndrome (PMS)

is a common hormone related condition which typically commences ten days prior to menses and resolves with the start of menstruation. It is most prevalent in women between the ages of 30 and 45 who may experience a variety of recurrent symptoms, including lethargy, depression, mood changes, cramping, and breast tenderness.₁₀₁
The major cause of this condition is poor dietary habits, lack of proper nutrition, and insufficient exercise. Essentially, it is a lifestyle related ailment.

A study determined that PMS patients consumed 62% more refined carbohydrates, 275% more refined sugar, 79% more dairy products, and 78% more sodium compared to symptom free women.₁₀₂

Factor Ten: Femtrac contains the specific blend of Vitamin B2, magnesium, folic acid, and L-tyrosine, which have been shown to alleviate lethargy, depression and mood swings. Black cohosh relieves cramping and Ginkgo biloba is effective in reducing breast tenderness.

In uncontrolled studies, PMS patients given supplements containing the combination of nutrients provided in Factor Ten: Femtrac showed a 70% reduction in both pre- and post- menstrual symptoms.₁₀₃, ₁₀₄

It is further suggested that patients experiencing the specific recurrent PMS signs of nervous tension, irritability and/or depression be placed on Factor Six: Sommaserene in the label dosages recommended.

Perimenopause

is the transition period from regular ovulatory cycles to menopause which usually begins at the age of 43 approximately five to seven years before a woman's final menses. As estrogen levels begin to decrease in anticipation of menopause, many women experience weight gains.

Factor Ten: Femtrac contains nutrients that elevate resting metabolism, increase the thermic effect of food, promote efficient burning of fat, facilitate ideal blood glucose levels and improve glycogen storage in muscles while reducing the desire for "sweets"

It is further recommended that female patients experiencing a weight problem incorporate Factor Eight: Natura Cleanse into their nutrition program as this supplement provides the fiber and related nutrients to facilitate weight control.

During perimenopause collagen production also drops with subsequent decreased skin elasticity and dryness of mucosal surfaces. These conditions are normal occurrences until hormonal balance has been achieved following perimenopause.

Factor Ten: Femtrac incorporates zinc, chromium, Vitamin P, and the amino acid L-lysine to assist in collagen formation and promote healthy skin tissue.

Menopause

the cessation of menses, is defined as the absence of menstrual bleeding due to loss of ovarian function. A common misconception is that menopause occurs when the female body fails to produce estrogen. In fact, the hormonal output of both estrogen and progesterone alternately stop and start instead of reducing gradually. This readjusting of the patient's endocrine balance leads to many of menopause's symptoms.₁₀₅

These symptoms of vasomotor instability include hot flashes, night sweats, palpitations, nausea, weakness, loss of libido, and headaches until hormone levels stabilize themselves. It is a natural part of a woman's aging process and usually begins at age 50 and lasts up to five years. Essentially, it is a stage of life, perhaps complicated by poor lifestyle choices, but not a disease.

The estrogen supply eventually regulates itself and reaches a plateau, where it remains until around age seventy. Although estrogen levels drop during the postmenopausal period, the hormone does not disappear.

The goal of a menopausal health program should be twofold:

First, to eliminate the bothersome symptoms of menopause by consuming estrogenic nutrients to help even out estrogen levels when needed.₁₀₆ This can be accomplished with Factor Ten: Femtrac as a mainstay and encouraging the patient to consume foods rich in phytoestrogens such as apples, carrots, yams, green beans, peas, red beans, brown rice, whole wheat, soy products, sesame seeds and papaya.₁₀₇

Second, to prevent the degenerative ailments of osteoporosis and heart disease that are associated with the postmenopausal period. This can be accomplished by supplementing the patient's diet with Factor Five: Osteo-X to prevent osteoporosis, and Factor One: Bio-Immunizer, to prevent heart disease.₁₀₈

Rejuvenation and Body Enhancement.

 

It is now clear, from hundreds of clinical studies and worldwide scientific research, that nutritional supplementation offers an amazingly effective and low-risk approach to alleviating the female problems associated with the endocrine and reproductive systems as well as achieving optimum health and body enhancement - without drugs or surgery!

Regardless of genetic background, optimal nutrition can slow or delay the aging process and help the patient improve on whatever normal life span her ancestors have experienced because the symptoms of aging are very similar to the symptoms of poor nutrition.₁₀₉

For example, the skin problems that are common in the elderly are nearly identical to the skin problems found in malnourished people.₁₁₀

Skin, hair, and nails are entirely composed of substances found in the diet. Many nutrient deficiencies show up first in the skin region. If the body must make a choice between using a nutrient for survival and using that nutrient to maintain a healthy glowing complexion, the skin loses!

The female body did not evolve to thrive on a continuous stream of refined sugar, hydrogenated fat, salt, pastries, bleached white flour and rice, cola drinks and high fat beef.

The U.S. Nationwide Food Consumption Survey revealed that 90 percent of Americans show some symptoms of malnutrition!₁₁₁ This downward spiral in "life force" is insidious because it occurs gradually over a prolonged period of time. Many individuals live their entire lives in this compromised state.

Factor Ten: Femtrac is targeted to treat the female health problems created by today's "modern lifestyle". It is specifically formulated to provide a woman's body with the nutrients necessary to withstand the onslaught of environmental pathogens and neutralize and eliminate the harmful substances that impair her body's power to heal itself.

Vaginitis & Related Infections.

 

A study reported that 72% of sexually active females had one or more forms of vaginitis.₁₁₂

Hormonal or atrophic vaginitis is primarily a problem of postmenopausal women and those whose ovaries have been surgically removed. The vaginal tissue becomes thin and susceptible to irritation and there may also be vaginal discharge.₁₁₃

Infectious vaginitis may be sexually transmitted or may arise from a disturbance to the ecology of the healthy vagina. Influencing factors include immune dysfunction, nutritional deficiencies, steroid medications, or diabetes mellitus.

Candida albicans or yeast infection has increased 250% since the late 1960's due primarily to the increased use of antibiotics and oral contraceptives. Primary symptoms are vulval itching which can be quite severe, and a thick, curdy discharge.₁₁₄ Factor Ten: Femtrac in combination with Factor One: Bio-Immunizer, together with a balanced diet low in fats and sugars, provide nutritive support for the relief of vaginal infections.

Additional Recommendations for Relief from Vaginitis.

1) Avoid the use of corticosteroids or oral contraceptives until condition improves.₁₁₅

2) Avoid pantyhose and tight undergarments made of synthetic fabrics which reduce air circulation at the vagina, causing over-warmth and perspiration.₁₁₆

3) Add three to four cups of pure apple cider vinegar to the bathwater and soak in the tub for twenty minutes.₁₁₇

4) Use a new toothbrush every 30 days as a preventive measure against fungus and bacterial infections.₁₁₈

5) Insert capsules of boric acid into the vagina. This treatment offers an inexpensive, easily accessible therapy which has proven to be equal to or better than those of Nystatin.₁₁₉

6) Practice relaxation techniques. Internalized stress can depress the immune system and aggravate infection.₁₂₀

7) Take antioxidant supplements, such as Factor One: Bio-Immunizer, that provides nutritive support to fight infection by destroying free radicals that depress the immune system.₁₂₁

Conventional approaches to women's health frequently use invasive medical procedures to deal with common physiological functions when therapeutic approaches such as diet nutritional supplementation, and herbal medicine are safer and frequently more effective.₁₂₂

The holistic practitioner has a responsibility to assure that his or her female patients have the necessary information to make informed choices about their lifestyle and health care.

Recommendations To achieving and Maintaining Optimum Vitality, Health, and Beauty

1) Supplementation. Take Factor Ten: Femtrac as a female health tonic in the dosage recommended.

2) Exercise Aerobically. Regular aerobic exercise - such as walking, jogging, dancing, tennis, bike riding, swimming - lowers blood pressure, fats in the blood and pulse rate while improving blood glucose, alertness, self-image, absorption of nutrients, and life span.₁₂₃

Aerobic exercise "activates" the nutrients in Factor Ten: Femtrac and elevates basal metabolism to burn stored fat more quickly.

3) Attitude. The mind is a potent determinant of the quality and quantity of a life. Social networking, and the extent of an individual's friends and relationships, is a major predictor of life span.₁₂₄

Your patients' attitudes also influence whether they will make exercise fun or whether they are amenable to changing their diet.

4) Eat foods as close to their natural state as possible. There are over 2,800 FDA-approved additives with another 10,000 additives being "incidental" to the agriculture and food processing industry.₁₂₅

5) Avoid foods cured with nitrite preservatives such as luncheon meat, bacon, corned beef or smoked or cured meats.

 

6) Eat a wide variety of foods. Individuals who eat a varied diet have a better nutrient intake than those whose diet remains staid.₁₂₆

7) Eat fish on a consistent basis. Individuals who eat at least two ounces of fish per week cut their heart disease risk in half.₁₂₇

8) Balance the Diet. The patient's diet should be balanced with the correct ratio of protein to fats to carbohydrates. Daily calories should be comprised of about 20% protein, 20 to 25% fat, and 55 to 60% carbohydrate, preferably complex carbohydrate.

9) Drink 6 to 8 glasses of water daily. Water suppresses the appetite naturally and helps the body metabolize stored fat. Studies have shown that a decrease in water intake will cause fat deposits to increase, while an increase in water intake can actually reduce fat deposits.

Water also helps to prevent sagging skin because cells are buoyed by water, which plumps the skin and leaves it clear, healthy and resilient.₁₂₈

10) Take an antioxidant supplement, such as Factor One: Bio-Immunizer, to boost natural immunity, destroy free radicals, and facilitate the body's ability to bring oxygen to the muscles.₁₂₉

11) Maintain ideal body fat composition. The quantity of weight has no bearing on health, per se.₁₃₀ With proper diet and exercise, heavier muscle mass begins replacing lighter fatty tissue and the patient begins to look and feel better as body composition improves.

Ideal body fat percentage range for women, regardless of age, is between 19 and 26 percent.

12) Avoid Diet Scams. Most heavily advertised diet programs are either low-carbohydrate, high protein, or drug dependent programs that "trick" the body into losing water weight quickly.₁₃₁ The results are temporary and often dangerous. The patient must understand she is trying to lose excess stored body fat, not lean muscle tissue and water.

 

13) Behavior Modification. There is a strong relationship between hours of TV watched and incidence of obesity.₁₃₂ TV viewing burns almost no calories, puts the viewer into a trance-like state of mind, and encourages frequent trips to the refrigerator.

The typical American eats no breakfast, a small lunch, and a huge dinner which is conducive to fat storage and poor health. Individuals who eat several small meals a day rather than one large meal at dinner are less likely to have weight problems.₁₃₃

14) Nutrition Modification. The majority of each meal should consist of carbohydrates such as whole grains, pasta, legumes, fruits and vegetables. A low-fat, high carbohydrate diet will produce quicker and more long-lasting weight loss.₁₃₄

15) Increase Fiber Consumption. Fiber is the "wonder nutrient" in weight control by providing oral and intestinal satiety without calories.₁₃₅ It binds fats, cholesterol and harmful metals and prevents them from being absorbed. Consider supplementing the diet with Factor Eight: Natura Cleanse, a natural intestinal toxicity cleanser and cholesterol reducer which promotes proper digestion.

16) Maintenance of Stable Weight. It is important for the patient to lose excess body fat and maintain a stable weight at a more desirable level.

A 1992 study of 11,703 Harvard graduates found that the lowest death rate was among those who maintained a stable weight, defined as plus or minus 2.2 pounds. Those who repeatedly gained or lost more than 10 pounds had higher death rates from all causes except cancer.₁₃₆

17) Reduce Caffeine Consumption. The intake of caffeine directly influences the prevalence and severity of PMS.₁₃₇ Caffeine intake, which includes coffee, tea, and cola, is also a risk factor in fibrocystic breast disease.₁₃₈

18) Reduce sugar consumption. Sugar causes a loss of magnesium from the body which is definitely related to PMS.₁₃₉ Sugar also stimulates the production of greater amounts of insulin, which promotes fluid retention.

19) Reduce alcohol consumption. Alcohol promotes nutritional deficiencies and lowers blood sugar. Two-thirds of the alcoholic women studied could relate their drinking bouts to PMS symptoms during their menstrual cycle.₁₄₀

20) Avoid Chocolate. Chocolate contains the compound Phenylethylamine which causes the blood vessels in the head to enlarge and places pressure on the surrounding brain tissue, resulting in possible headaches and migraines.₁₄₁

21) Take a Cal-Mag based supplement, such as Factor Five: Osteo-X for the relief of heartburn, nausea and/or motion sickness.

22) Take an herbal relaxant, such as Factor Six: Sommaserene, to alleviate anxiety, nervous tension, and irritability.

With adherence to the recommendations and suggestions set forth above, there is no reason to assume that menopause signals the end of an active, healthy life.

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FACTOR TEN FORMULATION
Two Capsules Equal:

Validation of Ingredients

VITAMIN B-1 (THIAMIN) plays a major role in the conversion of blood glucose into biological energy. Thiamin enhances both blood formation and circulation, carbohydrate metabolism and learning capacity.₁ Thiamine is not stored in the body and must be supplied daily. As a result, body tissues deplete rapidly when a deficiency occurs.₂

 

Eating sugar, smoking, and drinking alcohol will cause a thiamine depletion. Thiamine is also vulnerable to heat, air, and water in cooking.₃ Thiamine requirements during intense exercise increase 15-fold.₄ In fact, the exhausted athlete shows significantly lower levels of thiamine than a normal person.₅ There are probably more women deficient in Thiamin than any other vitamin.

 

VITAMIN B-2 (RIBOFLAVIN) is necessary for red blood cell formation, antibody production, cell respiration, and the normal release of energy from carbohydrate, protein, and fat in food. It also has antioxidant qualities and protects against free-radical damage.₆

 

Riboflavin is not stored in significant quantities in the body and must be replaced continuously through diet or supplementation to avoid deficiency. People who indulge in physical exercise often need extra riboflavin - particularly women.₇

 

A lack of stamina and vigor, retarded growth, digestive disturbances and impaired lactation are results of a riboflavin deficiency.₈

 

VITAMIN B-6 (PYRIDOXINE) is necessary for the formation of prostaglandins that regulate blood pressure, muscle contraction, and heart function. Pyridoxine aids in the regulation and maintenance of a healthy immune system.₉ It also promotes the production of the neurotransmitter serotonin that regulates sleep, pain, mood, and eating habits. Moods stabilize and depression is improved when Pyridoxine intake is increased.₁₀

 

The majority of clinical studies have demonstrated the efficacy of Pyridoxine supplementation in treating PMS.₁₁ In a double-blind cross-over trial, 84% of the subjects had a lower symptomatology score during the B-6 treatment period.

 

In another study, premenstrual acne flare-up was reduced in 72 percent of 106 affected young women taking 50 mg pyridoxine daily for one week prior and during the menstrual period.₁₂

 

It is important to note that some double-blind PMS studies of Pyridoxine have proven negative, in some cases as a result of the inability of some women to convert B-6 to its active form due to a deficiency in Riboflavin.₁₃ It is therefore imperative that both vitamins are present in any formulation for the amelioration of PMS.

 

Pyridoxine deficiency is common in women, individuals on restricted diets, individuals who consume diets high in sugar and fat, and women on oral contraceptives.₁₄

 

VITAMIN B-12 (CYANOCOBALAMIN) is necessary for normal processing of carbohydrate, protein, and fat in the body. This vitamin functions in the replication of the genetic code within each cell and is essential for the replacement and maintenance of all cells in the body.₁₅

 

The first symptoms of a B12 deficiency usually surface as irritability, impatience, and forgetfulness. In fact, some elderly manic patients have been found to have nothing more than a serious B12 deficiency.₁₆

 

Researchers have found that by depriving the microorganism Euglena of its vitamin B12, they can duplicate the effects of aging in human cells.₁₇

 

VITAMIN E (D-ALPHA TOCOPHEROL) is an antioxidant that improves circulation, repairs tissue, promotes normal clotting and healing and improves athletic performance.₁₈

 

Vitamin E can aid in the prevention of premature aging because of its role as an antioxidant. Free radicals destroy connective tissues that provide firmness to tissues such as the skin.₁₉

 

Vitamin E has been found useful in treating fibrocystic breast disease and PMS. Seventy-five women with fibrocystic breasts and PMS were given vitamin E in double-blind fashion. After two months of therapy, in varying levels of intake, 300 I.U.'s of vitamin E daily proved to substantially relieve breast tenderness and other symptoms of PMS.₂₀ A follow-up study found the same results.₂₁

 

FOLIC ACID (FOLACIN) is considered a brain food and is vital for healthy cell division and replication and may also help depression and anxiety.₂₂

 

Women who take folic acid show less precancerous cervical tissue as compared to women who consume a diet low in this vitamin. Folic acid may prevent the transformation of abnormal cells to cancer cells.₂₃

 

A deficiency of folic acid results in graying hair and gastrointestinal-tract disturbances, yet surveys show that the folic acid content of the American diet is half the recommended dietary intake.₂₄

 

BIOFLAVONOIDS (Vitamin P) are a group of vitamin-like nutrients which are found in fruits and vegetables and promote plant photosynthesis. Their components are citrin, rutin, hesperidin, flavones, and flavonals. They assist in keeping collagen in healthy condition.₂₅

 

In France, bioflavonoids have been used successfully for a number of women's gynecological problems. Physicians have found the flavone compounds effectively replace hormone therapy in cases of irregular or painful menstrual flow not caused by anatomical damage.₂₆

 

Bioflavonoids are estrogenic and help even out estrogen levels when needed, reducing the body's own synthesis of estrogen or binding with estrogen receptor sites to increase the body's estrogen when low.₂₇

 

POTASSIUM CHLORIDE is necessary to preserve proper alkalinity of the body fluids which aids in keeping the skin healthy.₂₈

 

Potassium assists in the conversion of glucose to glycogen, the form in which glucose can be stored in the liver. It also stimulates the kidneys to eliminate poisonous body wastes.₂₉

 

Potassium is effective at lowering blood pressure because it competes with sodium in the kidneys for reabsorption; it dilates blood vessels; and it reduces the flow of stress hormones (catecholamines) that can elevate blood pressure.₃₀

 

Potassium stimulates nerve impulses for muscle contraction and works with B-6, magnesium, zinc and red raspberry leaf to ameliorate severe menstrual cramps (Dysmenorrhea).₃₁

 

MAGNESIUM CHELATE functions in muscle relaxation and contraction, nerve transmission, and activates enzymes necessary for the metabolism of carbohydrates and amino acids. This essential mineral aids in the prevention of heart disease by protecting the arterial lining from stress caused by sudden blood pressure changes.₃₂

 

Magnesium deficiency is strongly implicated as a causative factor in premenstrual syndrome.₃₃ The deficiency is characterized by excessive nervous sensitivity, with generalized aches and pains and a lower premenstrual pain threshold.₃₄,₃₅

 

PMS patients given a multivitamin and mineral supplement containing magnesium and pyridoxine in an uncontrolled study showed a 70 percent reduction in both pre- and post- menstrual symptoms.₃₆Some women who experience head-ache, dizziness, and craving for sweets may respond to magnesium supplementation.

 

Many women do not consume the RDA's for magnesium (350 mg) and it is suspected that even the RDA's may not be optimal.₃₇ Lifestyle factors, such as physical or emotional stress, further increase the need for magnesium.

 

ZINC PICOLINATE is required for protein synthesis and collagen formation. Stretch marks in the skin may be signs of a zinc deficiency. Brittle nails and hair, and hair lacking pigment are also indications of a zinc deficiency.₃₈

 

Zinc has a beneficial effect on the immune system and the body's natural defense against colds, infection, and disease as it inhibits the growth of disease-causing bacteria. Zinc supplementation has been found effective in inhibiting several varieties of vaginal and yeast infections.₃₉,₄₀

 

Zinc helps eliminate cholesterol deposits and also aids in the proper growth and maturity of the sex organs. Irregular menstrual cycles in teen women is an indication of a zinc deficiency.₄₁

 

Zinc deficiency is common in the majority of the U.S. population because of soil exhaustion and the processing of food adversely affects zinc content.₄₂

 

CHROMIUM (Trivalent) is an essential mineral involved in the metabolism of glucose for energy and the synthesis of fatty acids and cholesterol. Chromium helps to regulate sugar levels in the blood. It appears to increase the effectiveness of insulin and its ability to handle glucose, preventing hypoglycemia (too much insulin) or diabetes (too little insulin).₄₃

 

Poor dietary intake of chromium results in limited availability of glucose tolerance factor (GTF) and impaired insulin activity. Blood sugar remains elevated and a diabetes-like condition similar to Type II Adult Onset develops.₄₄

 

As many as 90 percent of all American diets are low in chromium, because (1) soil depletion; (2) refined foods; (3) excessive sugar consumption; (4) lack of exercise; and (5) obesity. As a result, the diabetes rate has tripled since 1958 and now accounts for 15 percent of the nation's health care budget.₄₅

 

Chromium and zinc are weak links in the training of many athletes. Active individuals experience a seven to twenty fold increase in their glucose metabolism with measurable losses in chromium and zinc.₄₆

 

Chromium is also effective against acne. A variety of studies indicate that erratic blood glucose is tied to acne problems. When patients were given 400 mcg of chromium, the improvement in acne was rapid in most subjects.₄₇

 

L-LYSINE (AMINO ACID) is an essential building block which promotes collagen formation and helps build muscle protein. Antidotal evidence suggests this amino acid inhibits the herpes virus but no solid research exists to support this claim.₄₈

 

L-lysine, in combination with vitamins B-1 and B-6, can be utilized by the body to manufacture L-Carnitine. This amino acid aids in weight loss and improves athletic ability.₄₉

 

L-TYROSINE (AMINO ACID) suppresses appetite, reduces body fat, and acts as a mood elevator. This amino acid provides the raw materials for dopamine and noradrenaline (two vital chemicals for thought and emotions) in the brain. Low levels of tyrosine have been found in depressed patients.₅₀ L-Tyrosine has been effective in clinical trials in treating certain types of PMS depression.

 

BLACK COHOSH (CIMICIFUGA RACEMOSA EXTRACT) was introduced to American medicine by the Indians, who called it squaw root in reference to its use in relieving menstrual cramps and menopause. Recent scientific investigation has upheld this use. Clinical studies show it promotes and/or restores healthy menstrual activity; soothes irritation and congestion of the uterus, cervix, and vagina; relieves hot flashes and vaginal atrophy; and promotes uterine recovery.₅₁,₅₂,₅₃

 

Black Cohosh extract is an antispasmodic and estrogen enhancer. When compared in a clinical study with estrogen replacement as a treatment for menopausal symptoms after hysterectomy (with intact ovaries), it was shown to be as effective as synthetic hormones.₅₄

 

GINKGO BILOBA (GINKGOLIDE EXTRACT) is the world's oldest living tree species and can be traced back to the oldest Chinese materia medica (2800 B.C.). Ginkgo possesses compounds known to have therapeutic value in increasing blood flow to the brain thus helping memory loss, as well as age-related cerebral disorders.₅₅

 

Researchers have concluded that ginkgo is effective against the congestive symptoms of PMS, particularly breast pain or tenderness. Patients taking the ginkgo also noted improvements in neuro-psychological assessments.₅₆

 

ANGELICA SINENSIS (DONG QUAI) has been used in traditional oriental medicine for thousands of years, mainly for female disorders. It is well known in the United States as a women's tonic, primarily to adjust menstrual irregularities such as infrequent menstruation and abnormal menstrual bleeding.₅₇

 

Angelica sinensis is estrogenic and thought to reduce the frequency of hot flashes. Japanese women include this herb in their diet and have far fewer hot flashes than American women.₅₈,₅₉

 

Angelica sinensis root has demonstrated immuno-stimulating activities which include the induction of interferon production, stimulation of immune cell proliferation and anti-tumor activity.₆₀ In a Chinese study, the herb improved impaired liver functions of 60% of the patients with chronic hepatitis or cirrhosis of the liver. Many patients also experienced an improved blood count.₆₁

 

LICORICE ROOT (GLYCYRRHIZA GLABRA) promotes estrogenic activity which has been clearly established by experimental investigation.₆₂,₆₃ In a study involving women experiencing infrequent menstruation, normal ovulation was success- fully induced by utilizing an extract of Licorice root.₆₄

 

Poor nutrition, vigorous physical work, and/or anxiety can induce adrenal stress resulting in fatigue, weakness, head-ache, numbness or dizziness. Licorice root increases the effectiveness of adrenal hormones circulating in the liver, including the sex hormones androgen and estrogen, and mimics the action of these hormones itself, thereby helping the body to overcome adrenal failure.₆₅,₆₆

 

The above studies suggest that Licorice root has good potential for maintaining and/or restoring hormonal and reproductive health. Additionally, Licorice root extract possesses substantial anti-inflammatory properties and is widely utilized to ameliorate stiff, inflamed and sore muscles and joints due to arthritis, rheumatism, and bursitis.₆₇,₆₈

 

European researchers concluded several decades ago that licorice root extract has none of the side effects associated with the use of cortisone and hydrocortisone drugs yet is every bit as effective.₆₉

 

SUMA (PFAFFIA PANICULATA EXTRACT) has been found to be one of the most effective herbs from the Amazon for female problems. Suma is classified as an adaptogen which exerts an overall normalizing effect on the body by increasing the body's resistance to adverse influences.₇₀

 

Two plant hormones found in Suma, sitosterol and stigmasterol, encourage estrogen production and accounts for it's use for correcting menopausal symptoms.₇₁

 

GOTA KOLA (CENTELLA ASIATICA EXTRACT) has been used as a medicine in India and the Indonesia islands since prehistoric times for wound healing.₇₂ Early pharmacological investigations of centella demonstrated that this herb does substantially hasten the healing of wounds.₇₃

 

Centella's complex actions have a multiphase effect on cells and tissues including stimulation of hair and nail growth₇₄; increasing the tensile integrity of the dermis₇₅; and increasing the formation of chondroitin sulfate in bone.₇₆

 

Extracts of Centella asiatica have demonstrated good results in the treatment of cellulite in a number of clinical studies.₇₇,₇₈ These positive effects appear to be related to the herbs ability to enhance connective tissue structure by acting directly on fibroblasts.₇₉

 

GINGER ROOT (ZINGIBER OFFICINALE) produces a generalized stimulant effect which diffuses slowly from the G.I. tract and gently energizes the blood. Ginger root helps the body recover from the effects of stress and fatigue more rapidly than otherwise.₈₀ It works indirectly to increase the availability of dietary nutrients for digestion and metabolism and will markedly facilitate the utilization of energy stores.₈₁

 

Ginger root ameliorates symptoms of nausea, motion sickness, vertigo, dizziness and stomach disorders.₈₂ In fact, ginger root can prevent motion sickness considerably better than the popular drug, Dramamine.₈₃ Ginger root also helps reduce serum cholesterol levels, which promotes long term circulatory improvement.₈₄

 

RASPBERRY LEAF (RUBUS IDAEUS), with a nutrient content of citric acid, pectin, silicon and vitamin D, promotes healthy nails, teeth, and skin.₈₅

 

Raspberry leaf's major impact on the female system can best be described as normalization as it tempers the effects of hormonal runaway such as might occur during menstruation.

 

One study showed that Raspberry leaf extract prevented the typical hyper-growth effects of chronic gonadotrophine on ovaries and uterus₈₆ while another study demonstrated that this herb will, in fact, relax uterine muscles.₈₇

 

RAW OVARY concentrate has been found in clinical observations to help those cells in the body that are similar to it since raw bovine ovary is organ-specific rather than species-specific.₈₈

 

RAW ADRENAL concentrate. Using radioactive isotope tracing, Dr. A. Kment of Germany discovered that glandular tissues such as adrenal were absorbed by the bloodstream and deposited for use and support in the corresponding glands of the recipient.₈₉

 

The glandulars utilized in this formulation have been processed at 37 degrees F in the raw state to preserve the maximum nutrients and proteins inherent in such glands.

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References

 

1. Lonsdale, D, et al., Am. J. of Clinical Nutrition, vol 33, pp. 205-211, 1980

2. Dunne, LJ, Nutrition Almanac, 3rd Ed, McGraw-Hill, p. 21, 1990

3. Ibid

4. Bicknell, F, et al., Vitamins in Medicine, Heinneman, London, 1945

5. Nijakowski, F, Aviation, Space, and Environmental Medicine, vol 17, p. 397, 1966

6. Kaul, L, et al., Nutrition & Cancer, vol 9, pp. 123-128, 1987

7. Hendler, SS, Doctor's Vit. & Min. Encyclopedia, Simon & Schuster, pp. 54-55, 1990

8. Dunne, LJ, Nutrition Almanac, 3rd Ed, McGraw-Hill, p. 24, 1990

9. Bassler, K, Int. J. of Vit Nutrition, vol 58, pp. 105-118, 1988

10. Bender, D, Neurochemistry, vol 6, pp. 297-321, 1984

11. Barr, W, Practitioner, vol 228, pp. 425-27, 1984

12. Piesse, JW, Int. Clinical Nutr. Rev., vol 4, pp. 51-81, 1984

13. Stokes, J, et al., Lancet, p. 1177, 1972

14. Somer, E, Essential Guide to Vit. and Min., Harper-Collins, p. 51, 1992

15. Somer, E, Essential Guide to Vitamins and Minerals, Harper Collins, NY, 1992

16. Groggans, FC, American Journal of Psychiatry, vol 141, p.300, Feb. 1984

17. Kobrosielski-Vergona, K, Age, vol 10, p. 11, 1987

18. Howard, L, Nutritional Research, vol 48, pp. 169-177, 1990

19. Wartanoxicz, M, et al., Annals of Nutritional Metabolism, vol 28, pp. 186-191, 1984

20. London, RS, et al., J. of the Am. College of Nutr., vol 3, p. 351, 1984

21. Ibid

22. Davis, R, et al., International Journal of Biochemistry, vol 20, pp. 133-39, 1988

23. Somer, E, Essential Guide to Vitamins and Minerals, Harper Collins, NY, 1992

24. Davis, A, Let's Get Well, Harcourt, Brace & World, NY, 1965

25. Dunne, LJ, Nutrition Almanac, 3rd Ed, McGraw-Hill, p. 60, 1990

26. Ibid, p. 61

27. Adam, JB, International J. of Cancer, vol 50, no. 6, pp. 854-858, April 1992

28. Dunne, LJ, Nutrition Almanac, 3rd Ed, McGraw-Hill, p. 84, 1990

29. Ibid

30. Lancet, p. 1308, June 8, 1985

31. Hoffmann, DL, et al., Alternative Medicine, p. 661, 1993

32. Hendler, SS, Doctor's Vit. & Min. Encyclopedia, Simon & Schuster, pp. 157-64, 1990

33. Abraham, G, et al., Am. J. of Clinical Nutr., vol 34, pp. 2364-66, 1981

34. Abraham, G, J. Repro. Medicine, vol 28, pp. 446-64, 1983

35. Piesse, JW, Int. Clinical Nutr. Review, vol 4, pp. 54-81, 1984

36. Goei, GS, et al., J. Repro. Medicine, vol 28, pp. 527-31, 1983

37. Somer, E, Essential Guide to Vit. and Min., Harper Collins, p. 82, 1992

38. Kirschmann, JD, Nutrition Almanac, 3rd Ed, McGraw-Hill, pp. 90-92, 1990

39. Greenberg, S, et al., Antimicrob. Agents Chemo., vol 27, pp. 953-57, 1985

40. Krieger, J, et al., J. Inf. Disease, vol 146, pp. 341-5, 1982

41. Kirschmann, JD, Nutrition Almanac, 3rd Ed, McGraw-Hill, p. 91, 1990

42. Garrison, R, et al., Nutrition Desk Reference, pp. 140-41, 1985

43. Kirschman, JD, Nutrition Almanac, 3rd Ed, p. 70, 1990

44. Somer, E, Essential Guide to Vit. and Min., Harper Collins, p. 94, 1992

45. Gavin, JR, Research Report, National Inst. of Diabetes, Nov. 1995

46. Anderson, RA, et al., Biological Trace Element Research, vol 6, p. 327, 1984

47. McCarty, Medical Hypotheses, vol 14, p. 307, 1984

48. Hendler, SS, Doctor's Vit. and Min. Encyclopedia, pp. 221-3, 1990

49. Balch, JF, Prescrip. for Nutr. Healing, Avery Publishing, NY, p. 28, 1990

50. Kishimoto, H, et al., Yokohama Medical Bulletin, vol 27, p. 89, 1976

51. Porcher, FP, Transactions of the American Medical Association, vol 2, 1849

52. Millspaugh, CF, American Medicinal Plants, Dover Pub, NY, 1982

53. Felter, HW, Eclectic Materia Medica, Eclectic Med. Pubs, Portland, OR, 1983

54. Heron, S, Botanical Pharmaceuticals, Sedona, Nov. 3, 1989

55. DeFeudis, FV, Pharmacology Activities and Clinical Applications, Elsevier, Paris, 1991

56. Tamborini, A, et al., Rev Fr Gynecology Obstetric, vol 88, pp. 447-57, 1993

57. Keville, K, The Herb Encyclopedia, Grange Books, London, p. 38, 1991

58. Dodds, EC, et al., Nature, vol 139, pp. 627-28, 1937

59. Lark, Alternative Medicine, Future Medicine Publishing, WA, p. 664, 1993

60. Yamada, H, et al., Planta Medica, vol 56, pp. 182-86, 1990

61. Chang, HM, et al., Advances in Chinese Medicinal Research, World Scientific Pub. Co, Singapore, 1985

62. Sharaf, A, et al., Egyptian J. of Pharmaceutical Science, vol 16, no 2, pp. 245-51, 1975

63. Costello, CH, et al., J. of the American Pharmaceutical Assoc., vol 39, pp. 177-80, 1950

64. Yaginuma, T, et al., Nippon Sanka Fujinka Gakkai Zasshi, vol 34, no 7, pp. 939-44, 1982

65. Tamura, Y, Folia Endocrinologia Japonica, vol 8, pp. 164-88, 1975

66. Armanini, D, et al., Clinical Endocrinology, vol 19, no 5, pp. 609-12, 1983

67. Tangi, KK, et al., Biochemical Pharmacology, vol 14, no 8, pp. 1277-81, 1965

68. Cappelletti, EM, et al., J. of Ethnopharmacology, vol 6, no 2, pp. 161-90, 1982

69. Finney, SH, et al., J. of Pharmacology and Pharmacodynamics, vol 10, no 10, 613-20, 1958

70. DeOliveira, F, Rev. Bras. Farmacog., vol 1, no. 1, pp. 86-92, 1986

71. Schwontkowski, D, Healthy & Natural Journal, 1995

72. Kartnig, T, Herbs, Spices, Med Plants, vol 3, pp. 146-73, 1988

73. Boiteau, P, et al., Therapie, vol 11, pp. 125-49, 1956

74. Monograph: Centella asiatica. Indena.SpA, Milan, Italy, 1987

75. Ibid

76. Lawrence, JC, Journal of Investigative Dermatology, vol 49, pp. 95-6, 1967

77. Keller, F, et al., Med Hyg, vol 41, pp. 1513-18, 1983

78. Grosshans, E, et al., Journal Med Strasbourg, vol 14, pp. 563-67, 1983

79. Ippolito, F, G Ital Dermatology, vol 112, pp. 377-81, 1977

80. Suzuke, Y, et al., Folia Pharmacologia Japonica, vol 75, no 7, pp. 731-46, 1979

81. Thompson, EH, et al., J. of Food Science, vol 38, no 4, pp. 652-55, 1973

82. Mowrey, DB, et al., The Lancet, pp. 655-57, Mar. 20, 1982

83. Ibid

84. Gujral, S, et al., Nutrition Reports International, vol 17, no 2, pp. 183-89, 1978

85. Balch, JF, Prescription for Nutritional Healing, Avery Pub, NY, p. 57, 1990

86. Tangri, KK, et al., Biochemical Pharmacology, vol 14, no 8, pp. 1277-81, 1965

87. Nikitina, SS, Farmakologiiia i Toksikologiia, vol 29, no 1, pp. 67-70, 1966

88. Balch, JF, Prescription for Nutritional Healing, Avery Publishing Group, Garden City Par, NY, p. 326, 1990

89. Ibid.

 

Validation of Holistic Recommendations

 

90. Hughes, CL, Environ Health Perspect, vol 78, pp. 171-4, 1988

91. Beckham, N, Menopause - a positive approach using natural therapies, Viking/Penguin, Melbourne, 1995

92. Neil, K, Balancing Hormones Naturally, Ion Press, London, England, 1994

93. Ghamdi, M, et al, Am. J. Kidney Disease, vol 24, no 5, pp. 737-52, 1994

94. Lawrence, JC, J. of Investigative Dermotol,, vol 49, pp. 95-6, 1967

95. Beckham, N, Ibid.

96. Archer, J, Bad Medicine, Simon & Schuster, Australia, 1995

97. Welshons, WV, et al, Breast Cancer Research and Treatment, vol 10, pp. 169-75, 1987

98. Beckham, N, Aust. J. Med. Herbalism, vol 7, no 1, 1995

99. Herbal Medicines: A guide for Health Care Professionals, The Pharmaceutical Press, London, 1996

100. Phytoestrogens for Menopausal Complaints, Phyto-Pharmacia Review, Bellevue, WA 1991

101. Abraham, GE, J. Repro. Medicine, vol 28, pp. 446-64, 1983

102. Ibid

103. Piesse, JW, Int. Clin. Nutr. Review, vol 4, pp. 54-81, 1984

104. Goei, GS, J. Repro. Medicine, vol 28, pp. 465-68, 1983

105. Alternative Medicine, Future Med. Pub., Puyallup, WA, p. 664, 1993

106. Wilcox, G, et al, British Medical Journal, vol 301, no 6757, pp. 905-06, Oct 1990

107. Ibid.

108. Prince, RL, et al, New England J. of Medicine, vol 325, no 17, pp. 1189-95, Oct 1991

109. Neldner, KH, Geriatrics, vol 39, p. 69, Feb. 1984

110. Ibid

111. Lowenstein, FW, Bibliotheca Nutrition et Diets, vol 30, 1991

112. Woo, B, et al., Office Practice of Medicine, W.B. Saunders, PA, pp. 461-70, 1982

113. Murray, MT, et al., Encyclopedia of Natural Medicine, Prima Publishing, Rocklin, CA, p. 526, 1991

114. Larsen, B, et al., Ob. Gyn., SS supplement, pp. 1005-135, 1980

115. Ibid

116. Murray, M, et al., Encyclopedia of Natural Medicine, Prima Pub., Rocklin, CA, p. 528, 1191

117. Heidrich, F, et al., J. Family Practice, vol 19, pp. 491-94, 1984

118. Balch, JF, Prescrip. for Nutritional Healing, Avery Pub., Garden City Park, NY, p. 307, 1990

119. Ibid

120. Keller, VK, et al., Am. J. Ob. Gyn., vol 141, pp. 145-48, 1981

121. Locke, S, et al., Foundations of Psychoneuroimmunology, 1985

122. Weil, A, Natural Health, Natural Medicine, Houghton Mifflin Co., Boston, p. 174, 1990

123. Taylor, CB, et al., Public Health Reports, vol 100, no 2, p. 195, March 1986

124. Welin, L, et al., Lancet, p. 915, April 20, 1985

125. Long, P, et al., Nutrition: An Inquiry into the Issues, p. 389, 1983

126. Randell, E. et al., J. Am. Dietetic Assoc., Vol 85, p. 830, July 1985

127. Kromhout, D, et al., New England J. of Medicine, vol 312, p. 1205, May 9, 1985

128. Robertson, DS, The Snowbird Diet, Warner Books, 1988

129. Factor One: Bio-Immunizer, Research Report, Titan Publishing, New York, NY, 1998

130. Williams, E, et al., Biomarkers, p. 53-58, 1992

131. Yang, MU, et al., J. of Clinic Investigation, vol 58, p. 722, 1976

132. Dietz, WH, et al., Pediatrics, vol 75, p. 807, May 1985

133. Leveille, GA, et al., Nutrition Today, p. 4 Nov. 1974

134. Evans, W, et al., Biomarkers, pp. 221-30, 1992

135. Duncan, KH, et al., Am. J. of Clinical Nutrition, vol 37, p. 763, May 1983

136. Journal of the American Medical Association, Oct 20, 1992

137. Rossignol, AM, American J. of Public Health, vol 75, p. 1335, Nov 1985

138. Minton, JP, et al., Surgery, vol 86, p. 105, 1979

139. Frankel, TL, et al., British J. of Nutrition, vol 39, p. 227, 1978

140. Belfer, ML, et al., Archives of General Psychiatry, vol 25, p. 540, 1971

141. Cornwell, N, et al., Int. J. of Sports Medicine, vol 7, p. 307, 1986

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